Cell Therapy for Acute Liver Failure - Ideal source of cell
نویسندگان
چکیده
Liver is the central metabolic organ that regulates body’s energy supply, secretes several essential compounds and clears substances by several methods, including recycling, inactivation andexcretion. Global loss of the liver function results in profound metabolic instability and disruption of essential functions such as acid-base balance and thermoregulation leading to acute liver failure (ALF). If this is not rapidly reversed, complications such as uncontrolled bleeding occur, and dependent organs such as brain and kidneys begin to fail, reducing the chance of recovery even further. Acute liver failure (ALF) carries high morbidity and mortality (>80%) even in the best centres.
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